Product Description
Glutathione S-transferase (GST)
Glutathione S-transferase (GST, 2.5.1.*8) is generally polymerized
by two subunits of ****7kda in the same or different way (the
isoelectric point is pH**5). The N-terminal of its subunit has a
conserved serine / tyrosine (Ser / Tyr) residue. Its hydroxyl group
forms hydrogen bond with the sulfhydryl group of glutathione (GSH),
which is the specific binding site of GSH.
GST is a group of multi-functional isoenzymes widely distributed in
various organisms. It is a group of enzymes related to the
detoxification function of the liver, mainly in the liver, and
trace in the kidney, small intestine, testis, ovary and other
tissues. Its main function is to catalyze the sulfhydryl coupling
of some endogenous or foreign harmful substances with reduced
glutathione and increase its hydrophobicity It is easy to pass
through the cell membrane and be discharged from the body after
decomposition, so as to achieve the purpose of detoxification.
Because the cytoplasm of liver is rich in GST, when the liver cells
are damaged, the enzyme is released into the blood rapidly,
resulting in the increase of serum GST activity.
GST is often used in the construction of efficient expression
vector in gene engineering, so as to co express with some proteins
that are difficult to express as molecular chaperones, so as to
achieve a soluble expression. In addition, we often use GST
antibody to do Western Blot and other experiments to detect whether
to achieve gene co expression, so it is of great significance to
study it.
[Product Description]
Dosage form: white lyophilized powder or liquid
Preservation buffer: PBS buffer, pH7.0
General information:
Source: gene recombinant expression
Molecular weight: about *6kDa (detected by SDS-PAGE)
Purity: ≥ *0% (SDS-PAGE detection)
Storage conditions: freeze dried powder at 4 ℃ or long-term storage
at - *0 ℃
Transportation conditions: ice bag at low temperature
Safety tips: not for human experiment
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In Vitro Diagnostic Kit Raw Materials
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